The Electrostatic Potential for the two-states of the Human beta-2-Adrenergic Receptor



1A                                                                  1B


1A is the base state with the cysteine as S- and 1B is the acid state with the cysteine as SH. The large blue region at the bottom of the receptor is intracellular while the smaller red electronegative region is on the extracellular side of the receptor.



A close-up of the beta-2-adrenergic receptor surface showing the electronegative region in red that an incoming ligand would encounter.  The cysteine and aspartate residues of the third transmembrane region are exposed to show that the electronegative region surrounds these residues.



Graphical Pictures of the top face of the human beta-2-adrenergic receptor.





Graphical pictures of the side of the Human beta-2-adrenergic receptor and the electrostatic potential, which surrounds it.





Slab views through the side of the receptor:



*For the 5-HT2A receptor click here



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